Identification ofSchistosoma mansonigender-associated gene transcripts by cDNA microarray profiling

Parasitic helminths of the genusSchistosomamate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important pathological consequences of the infection are associated with this process. We have used cDNA microarray technology to initiate genome-wide gene-expression studies of sex and sexual development in matureSchistosoma mansoniparasites.