Isolation,in silicocharacterization and chromosomal localization of a group of cDNAs from ciliated epithelial cells afterin vitrociliogenesis

Immotile cilia syndrome (ICS) or primary ciliary dyskinesia (PCD) is an autosomal recessive disorder in humans in which the beating of cilia and sperm flagella is impaired. Ciliated epithelial cell linings are present in many tissues. To understand ciliary assembly and motility, it is important to isolate those genes involved in the process.