Patent AT-E400568-T1: [Translated] SUBSTITUTED 4-(4-PIPERIDINE-YL-PIPERAZINE-1-YL)-AZEPAN DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS

The invention concerns substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives having neurokinin antagonistic activity, in particular NK~antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment of pain, emesis, anxiety, depression and IBS.