Patent AT-E40127-T1: [Translated] 1,5-BENZOTHIAZEPINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND MEDICATIONS.

Novel 1,5-benzothiazepine derivatives of the formula:wherein R' and R⁴ are:a) R¹ is lower alkyl or lower alkoxy, and R⁴ is lower alkyl, lower alkoxy, fluorine, benzyloxy, hydroxy or lower alkylthio, orb) R' is lower alkyl, and R⁴ is hydrogen, orc) R' is hydroxy, and R⁴ is lower alkyl, fluorine, hydroxy or lower alkylthio;R² is hydrogen, lower alkanoyl or benzoyl; and R³ is lower alkyl; and a pharmaceutically acceptable acid addition salt thereof are disclosed. In form of pharmaceutical compositions the said derivative (I) and its salt have a potent platelet aggregation-inhibiting activity.