Patent AT-E401398-T1: [Translated] METHOD FOR PRODUCING POLYNUCLEOTIDE FRAGMENTS FOR USE IN SHUFFLING

The invention relates to a fragmentation process that depends on mismatches between two strands of parental polynucleotides. One embodiment, comprises a method for preparing polynucleotide fragments of DNA comprising formation of heteroduplex molecules by hybridizing polynucleotides. The invention also provides a method and process of forming fragments which can be used with any shuffling process or combination of shuffling processes.