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BLAST (Basic Local Alignment Search Tool) finds regions of similarity between biological sequences. BLAST includes several specialized search interfaces: SmartBLAST, Primer-BLAST, Global Align, CD-Search, IgBLAST,…
Updated Oct 29, 2026
HealthData.Gov
NCBI Datasets is one-stop shop for finding, browsing, and downloading genomic data. Find and download taxonomy, genome, gene, transcript, protein data, including installation of NCBI Datasets command-line tools.
Updated Oct 29, 2026
HealthData.Gov
A utility for computing alignment of proteins to genomic nucleotide sequence based on a variation of the Needleman Wunsch global alignment algorithm and specifically accounts for introns and splice signals.
Updated Oct 29, 2026
HealthData.Gov
The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein…
Updated Oct 29, 2026
HealthData.Gov
CDTree is a stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies,…
Updated Oct 29, 2026
HealthData.Gov
A collection of Reference Sequence (RefSeq) proteins, from the complete genomes of prokaryotes, plasmids, and organelles, that have been grouped and annotated based on sequence similarity and protein function.
Updated Oct 29, 2026
HealthData.Gov
A computer algorithm that identifies similar protein 3-dimensional structures. Structure neighbors for every structure in MMDB are pre-computed and accessible via links on the MMDB Structure Summary pages.
Updated Oct 29, 2026
HealthData.Gov
The Consensus CDS (CCDS) project is a collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated and of high quality. The long term goal is to support…
Updated Oct 29, 2026
HealthData.Gov
An interactive Web application that enables users to visualize multiple alignments created by database search results or other software applications. The MSA Viewer allows users to upload an alignment and set a master…
Updated Oct 29, 2026
HealthData.Gov
Three dimensional structures provide a wealth of information on the biological function and the evolutionary history of macromolecules. They can be used to examine sequence-structure-function relationships,…
Updated Oct 29, 2026
HealthData.Gov
Conserved Domain Database (CDD) is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins.
Updated Oct 29, 2026
HealthData.Gov
Users can display, sort, subset and download position-specific score matrices (PSSMs) either from CDD records or from Position Specific Iterated (PSI)-BLAST protein searches.
Updated Oct 29, 2026
HealthData.Gov
NCBI Virus is an integrative, value-added resource designed to support retrieval, display and analysis of a curated collection of virus sequences and large sequence datasets. Its goal is to increase the usability of…
Updated Oct 29, 2026
HealthData.Gov
Constraint-Based Multiple Alignment Tool (COBALT) is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and…
Updated Oct 29, 2026
