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Occupational exposure to 4,4’-methylene diphenyl diisocyanate (MDI), the most widely used monomeric diisocyanate (dNCO), is associated with occupational asthma (OA) development. Recruitment of immune cells to the lung…
Updated Oct 29, 2026
HealthData.Gov
Occupational immune diseases are some of the most common illnesses that affect workers in the United States. The Healthcare and Social Assistance Sector (HCSA) has one of the highest incidence of allergic disease…
Updated Oct 29, 2026
HealthData.Gov
Air pollution serves as a major risk factor for the development of asthma, respiratory disease and heart disease. Diesel particulate and fumes are a major contributor to air pollution. Workers in a number of different…
Updated Oct 29, 2026
HealthData.Gov
E-cigarettes utilize a wide range of flavoring chemicals whose respiratory health effects are not well understood. In this study, we used pulmonary-associated cell lines to assess the in vitro cytotoxic effects of…
Updated Oct 29, 2026
HealthData.Gov
Inhalation exposure to respirable crystalline silica (RCS) during fabrication of engineered stone-based kitchen countertops has been on the rise in recent years and has become a significant occupational health problem…
Updated Oct 29, 2026
HealthData.Gov
Exposure to multi-walled carbon nanotubes (MWCNTs) induces inflammation leading to chronic lesions in mammalian lungs. The inflammatory response to MWCNTs involves the polarization of macrophages to M1 and M2 cells that…
Updated Oct 29, 2026
HealthData.Gov
Exposure to hand-transmitted vibration (HTV) has been shown to result in cold-induced vasoconstriction and a reduction in blood flow to the hands and fingers of workers. Occupational exposure to HTV can also induce a…
Updated Oct 29, 2026
HealthData.Gov
Exposure to 4,4’-methylene diphenyl diisocyanate (MDI), the most used monomeric diisocyanate, can lead to the development of occupational asthma (OA). However, the detailed molecular pathophysiological mechanisms behind…
Updated Oct 29, 2026
HealthData.Gov
Nanomaterials represent a new class of materials with numerous industrial applications. Considering the projected increase in the production and use of nanomaterials, a corresponding increase in occupational exposure to…
Updated Oct 29, 2026
HealthData.Gov
The toxicity of boron nitride nanotubes (BNNTs) is confounded by the various manufacturing and purification strategies employed targeted to remove 30-60% of the residuals and impurities. Four BNNTs manufactured by the…
Updated Oct 29, 2026
HealthData.Gov
This dataset contains vaccine mandate prohibitions that were issued by 50 states, 5 territories, and the District of Columbia currently in effect. State and territorial laws are collected from publicly available…
Updated Oct 29, 2026
HealthData.Gov
Information on radiographic evidence of coal workers’ pneumoconiosis (CWP) is presented for a group of 3,194 underground bituminous coal miners and ex-miners examined between 1985 and 1988. Prevalence of CWP was related…
Updated Oct 29, 2026
HealthData.Gov
Per- and polyfluoroalkyl substances (PFAS) are a large group of synthetic man-made surfactants of over 12,000 compounds that are incorporated into numerous products for their chemical and physical properties. Numerous…
Updated Oct 29, 2026
HealthData.Gov
NNDSS - Table II. Tuberculosis - 2019. This Table includes total number of cases reported in the United States, by region and by states, in accordance with the current method of displaying WONDER data. Data on United…
Updated Oct 29, 2026
HealthData.Gov
: This dataset contains all vaccine mandate prohibitions that were issued as of , by 50 states, 5 territories, and the District of Columbia regardless of whether the law has been superseded by a subsequent law,…
Updated Oct 29, 2026
HealthData.Gov
Background: The purpose of this study was to estimate the incidence and prevalence of hearing loss for noise-exposed U.S. workers by industry sector and 5-year time period, covering 30 years. Methods: Audiograms for 1.8…
Updated Oct 29, 2026
HealthData.Gov
Supplies of N95® filtering facepiece respirators (FFRs) can become depleted during widespread outbreaks of infectious respiratory illnesses. To supplement the national inventory of NIOSH Approved® N95 FFRs during times…
Updated Oct 29, 2026
HealthData.Gov
Loading-induced hypertrophy with transcriptional upregulation has been observed concomitant with nuclei accretion in various studies regarding both humans and rodents. Bruusgaard et al. in 2010 pioneered work utilizing…
Updated Oct 29, 2026
HealthData.Gov
PFAS have been shown to activate peroxisome proliferator-activated receptor α (PPARα), a transcription factor involved in lipid metabolism. PFAS comprises a wide range of compounds, and variations in their structural…
Updated Oct 29, 2026
HealthData.Gov
The U.S. Food and Drug Administration (FDA) requires surgical masks (SMs) and surgical N95 respirators used in healthcare to meet certain fluid resistance and flammability levels. NIOSH’s National Personal Protective…
Updated Oct 29, 2026
