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The impact of genetic diseases on Jordanians: strategies towards prevention
The impact of genetic diseases on Jordanians: strategies towards prevention
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Updated Oct 29, 2026
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2,009 datasets
HealthData.Gov
Connexin-mimetic peptide Gap 27 decreases osteoclastic activity
Background Bone remodelling is dependent on the balance between bone resorbing osteoclasts and bone forming osteoblasts. We have shown previously that osteoclasts contain gap-junctional protein connexin-43 and that a…
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Updated Oct 29, 2026
HealthData.Gov
Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different SOFA scores during the course of sepsis and MODS
Objectives: The relation of procalcitonin (PCT) plasma concentrations compared with C-reactive protein (CRP) was analyzed in patients with different severity of multiple organ dysfunction syndrome (MODS) and systemic…
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Updated Oct 29, 2026
HealthData.Gov
The challenge of early synovitis: multiple pathways to a common clinical syndrome
The challenge of early synovitis: multiple pathways to a common clinical syndrome
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Updated Oct 29, 2026
HealthData.Gov
Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial [ISRCTN19943732]
The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council. When complete, it will be…
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Updated Oct 29, 2026
HealthData.Gov
Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand
Background Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce cytokines that direct T cell…
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Updated Oct 29, 2026
HealthData.Gov
The PRC-barrel: a widespread, conserved domain shared by photosynthetic reaction center subunits and proteins of RNA metabolism
The PRC-H β-barrel domain, a distinct cytoplasmic β-barrel domain whose fold has no close structural relationship to any other well known β-barrel domain, is the prototype of a novel superfamily of protein domains…
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Updated Oct 29, 2026
HealthData.Gov
Research Article: BMC Genomics
Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The regulatory mechanisms responsible for brain specificity…
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Updated Oct 29, 2026
HealthData.Gov
Annotated Bibliography on Equity in Health, 1980-2001
The purposes of this bibliography are to present an overview of the published literature on equity in health and to summarize key articles relevant to the mission of the International Society for Equity in Health…
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Updated Oct 29, 2026
HealthData.Gov
The MRC trial of assessment and management of older people in the community: objectives, design and interventions [ISRCTN23494848]
Background The benefit of regular multidimensional assessment of older people remains controversial. The majority of trials have been too small to produce adequate evidence to inform policy. Despite the lack of a firm…
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Updated Oct 29, 2026
HealthData.Gov
Serine / threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling
Background In most cells glucocorticoid receptors (GR) reside predominately in the cytoplasm. Upon hormone binding, the GR translocates into the nucleus, where the hormone-activated GR-complex regulates the…
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Updated Oct 29, 2026
HealthData.Gov
Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
Background Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate. Antibiotics are often prescribed…
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Updated Oct 29, 2026
HealthData.Gov
A new non-linear normalization method for reducing variability in DNA microarray experiments
A simple and robust non-linear method is presented for normalization using array signal distribution analysis and cubic splines. Both the regression and spline-based methods described performed better than existing…
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Updated Oct 29, 2026
HealthData.Gov
Diagnostic and treatment characteristics of polycystic ovary syndrome: descriptive measurements of patient perception and awareness from 657 confidential self-reports
Background This investigation was undertaken to describe patient perception and awareness of the polycystic ovary syndrome (PCOS), the most common cause of anovulation/oligoovulation among women of reproductive age.…
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Updated Oct 29, 2026
HealthData.Gov
Identification of bacteria in drinking and purified water during the monitoring of a typical water purification system
Background A typical purification system that provides purified water which meets ionic and organic chemical standards, must be protected from microbial proliferation to minimize cross-contamination for use in cleaning…
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Updated Oct 29, 2026
HealthData.Gov
The immunological effects of continuous veno-venous haemodiafiltration in critically ill patients
Background: Haemodynamic instability is common in septic patients with acute renal failure. Continuous veno-venous haemodiafiltration (CVVHD) is therefore used as an alternative to conventional haemodialysis.…
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Updated Oct 29, 2026
HealthData.Gov
Skeletal muscle dysfunction in chronic obstructive pulmonary disease
It has become increasingly recognized that skeletal muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Muscle strength and endurance are decreased, whereas muscle fatigability is…
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Updated Oct 29, 2026
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Expression and localization of estrogen receptor-β in annulus cells of the human intervertebral disc and the mitogenic effect of 17-β-estradiol in vitro
Background Recent evidence suggests that estrogens exert effects in different tissues throughout the body, and that the estrogen receptor β (ERβ) may be important for the action of estrogen (17-β-estradiol) on the…
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Updated Oct 29, 2026
HealthData.Gov
Efficacy and adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome
Background To investigate the effects of intravenous lignocaine infusions (IV lignocaine) in fibromyalgia. Methods Prospective study of the adverse effects of IV lignocaine in 106 patients with fibromyalgia;…
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Updated Oct 29, 2026
HealthData.Gov
Determination of PCR efficiency in chelex-100 purified clinical samples and comparison of real-time quantitative PCR and conventional PCR for detection of
Background Chlamydia pneumoniae infection has been detected by serological methods, but PCR is gaining more interest. A number of different PCR assays have been developed and some are used in combination with serology…
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Updated Oct 29, 2026