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ICU resource allocation: life in the fast lane
ICU resource allocation: life in the fast lane
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Updated Oct 29, 2026
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2,009 datasets
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Weather conditions and sudden sensorineural hearing loss
Background Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL). We investigated the seasonal distribution of ISSHL and evaluated…
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Updated Oct 29, 2026
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Mitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate
Background Thiamine diphosphate (ThDP) is the active form of thiamine, and it serves as a cofactor for several enzymes, both cytosolic and mitochondrial. Isolated mitochondria have been shown to take up thiamine yet…
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Updated Oct 29, 2026
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No effects on myocardial ischaemia in patients with stable ischaemic heart disease after treatment with ramipril for 6 months
Objective To assess the effects of a 6-month angiotensin-converting enzyme (ACE) inhibitor intervention on myocardial ischaemia. Method We randomized 389 patients with stable coronary artery disease to double-blind…
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Updated Oct 29, 2026
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Perturbations in the impact of mutational activity on Vλ genes in systemic lupus erythematosus
To assess the impact of somatic hypermutation and selective influences on the Vλ light chain repertoire in systemic lupus erythematosus (SLE), the frequency and pattern of mutations were analyzed in individual CD19+ B…
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Updated Oct 29, 2026
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A rapid method to map mutations in
Background Genetic screens in Drosophila have provided a wealth of information about a variety of cellular and developmental processes. It is now possible to screen for mutant phenotypes in virtually any cell at any…
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Updated Oct 29, 2026
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Erythropoietin, uncertainty principle and cancer related anaemia
Background This study was designed to evaluate if erythropoietin (EPO) is effective in the treatment of cancer related anemia, and if its effect remains unchanged when data are analyzed according to various clinical and…
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Updated Oct 29, 2026
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Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate and its relation to clinical variables in inflammatory arthritis
Hypothalamic–pituitary–adrenal underactivity has been reported in rheumatoid arthritis (RA). This phenomenon has implications with regard to the pathogenesis and treatment of the disease. The present study was designed…
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Updated Oct 29, 2026
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An efficient method to successively introduce transgenes into a given genomic locus in the mouse
Background Expression of transgenes in mice requires transcriptional regulatory elements that direct expression in a chosen cell type. Unfortunately, the availability of well-characterized promoters that direct…
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Updated Oct 29, 2026
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Severe renal bleeding caused by a ruptured renal sheath: case report of a rare complication of percutaneous nephrolithotomy
Background Percutaneous nephrolithotomy is a minimally invasive intervention for renal stone disease. Complications, which are rare and usually presented as case reports, are diversified as the utilization of the…
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Updated Oct 29, 2026
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Mycosin-1, a subtilisin-like serine protease of
Background Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in Mycobacterium tuberculosis. There are five genes (mycP1-5)…
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Updated Oct 29, 2026
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Epstein-Barr virus reactivation after superinfection of the BJAB-B1 and P3HR-1 cell lines with cytomegalovirus
Background Studies examining herpesvirus-herpesvirus (cytomegalovirus (CMV)-Epstein-Barr virus (EBV)) interactions are limited, and many of the studies have been clinical observations suggesting such an interaction…
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Updated Oct 29, 2026
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Clinical applicability of molecular biology: the case of the long QT syndrome
The clinical applicability of molecular cardiology has been questioned at length and by many clinical investigators. The congenital long QT syndrome (LQTS) provides an excellent example of how tight the relationship can…
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Updated Oct 29, 2026
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Research Article: BMC Pharmacology
Background Evidence suggests that both the migration and activation of neutrophils into the airway is of importance in pathological conditions such as pulmonary emphysema. In the present study, we describe in vivo…
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Updated Oct 29, 2026
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The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease
The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to the destruction of normal architecture and…
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Updated Oct 29, 2026
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Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development
Background Vertebrate neural development requires precise coordination of cell proliferation and cell specification to guide orderly transition of mitotically active precursor cells into different types of post-mitotic…
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Updated Oct 29, 2026
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The human olfactory receptor repertoire
Background The mammalian olfactory apparatus is able to recognize and distinguish thousands of structurally diverse volatile chemicals. This chemosensory function is mediated by a very large family of…
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Updated Oct 29, 2026
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Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival
Background We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell carcinoma. Methods Formalin-fixed and paraffin-embedded…
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Updated Oct 29, 2026
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New insights into the effects on blood pressure of diets low in salt and high in fruits and vegetables and low-fat dairy products
Results from the recent Dietary Approaches to Stop Hypertension (DASH)-Sodium trial provide the latest evidence concerning the effects of dietary patterns and sodium intake on blood pressure. Participants ate either the…
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Updated Oct 29, 2026
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Pervasive properties of the genomic signature
Background The dinucleotide relative abundance profile can be regarded as a genomic signature because, despite diversity between species, it varies little between 50 kilobase or longer windows on a given genome. Both…
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Updated Oct 29, 2026