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Silicosis is an irreversible occupational lung disease resulting from crystalline silica exposure. Previously, we discovered that Western diet (HFWD)-consumption increases susceptibility to silica-induced pulmonary…
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This noise database was developed to provide researchers and other interested stakeholders with noise measurement results that the National Institute for Occupational Safety and Health (NIOSH) has collected during…
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The goal of the experimental design and research presented herein was to produce peracetic acid (PAA) atmospheres suitable for evaluating PAA sampling methods in a controlled environment. To achieve this, generated test…
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Adipose tissue (AT), an endocrine organ, plays a central role in maintenance of whole-body energy homeostasis through its release of adipokines. Obesity, affecting over 40% of American adults, disrupts adipocyte…
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Occupational exposure to 4,4’-methylene diphenyl diisocyanate (MDI), the most widely used monomeric diisocyanate (dNCO), is associated with occupational asthma (OA) development. Recruitment of immune cells to the lung…
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The P2P Resource Center is a one-stop, easy-to-navigate website that features tools and resources produced by CDC-funded PRC research projects. Community organizations and public health practitioners can tailor these…
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In the lung, carcinogenesis is a multi-stage process that includes initiation by a genotoxic agent, promotion that expands the population of cells with damaged DNA to form a tumor, and progression from benign to…
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Occupational exposure to 4,4’-methylene diphenyl diisocyanate (MDI), the most widely used monomeric diisocyanate, is one of the leading causes of occupational asthma (OA). Pathophysiological mechanism(s) by which how…
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The fundamental goal of this study was to develop an in vivo model of the exposome that could be used to evaluate exposure-induced alterations in local and systemic immune markers as a function of various exposomal…
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We investigated the suitability of graphitic carbon (GC) content of diesel particulate matter (DPM), measured using Raman spectroscopy, as a surrogate measure of elemental carbon (EC), determined by thermal optical…
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Occupational immune diseases are some of the most common illnesses that affect workers in the United States. The Healthcare and Social Assistance Sector (HCSA) has one of the highest incidence of allergic disease…
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Interleukin (IL)-11, a pleiotropic, cationic cytokine, contributes to numerous biological processes, including adipogenesis, hematopoiesis, and inflammation. Asthma, a chronic respiratory disease, is notably…
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The accommodation of worker anthropometric variability in the workplace and personal protective equipment (PPE) is key to safe and efficient completion of work tasks. Previously, the best data available was 46 years…
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The demand for disposable respiratory protective devices needed to protect health care personnel may exceed supply during large outbreaks of respiratory infectious diseases. Concerns occurred over the global shortages…
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Diesel exhaust (DE) is an air pollutant containing gaseous compounds and particulate matter. Diesel engines are common on gas extraction and oil sites, leading to complex DE exposure to a broad range of compounds…
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: This dataset contains all vaccine mandate prohibitions that were issued as of , by 50 states, 5 territories, and the District of Columbia regardless of whether the law has been superseded by a subsequent law,…
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This dataset contains vaccine mandate prohibitions that were issued by 50 states, 5 territories, and the District of Columbia currently in effect. State and territorial laws are collected from publicly available…
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Exposure to certain engineered nanomaterials (ENMs) causes chronic lesions like lung fibrosis and cancer as a result of unresolved inflammation. Elucidating how ENM-induced inflammation is resolved is necessary for…
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Air pollution serves as a major risk factor for the development of asthma, respiratory disease and heart disease. Diesel particulate and fumes are a major contributor to air pollution. Workers in a number of different…
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The objective of this study was to evaluate the effect of a back-support exoskeleton (Laevo V2.5) on the trunk and hip angles, low back muscle activity, and heart rate during in-bed patient handling tasks. Eight…