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Background Oral anticoagulants like the coumarin derivatives are characterised by a particularly narrow therapeutic range. Any interfering co-medication can pose a challenge to establishing a stable anticoagulant dosage…
Updated Oct 29, 2026
HealthData.Gov
Background Better automation, lower cost per reaction and a heightened interest in comparative genomics has led to a dramatic increase in DNA sequencing activities. Although the large sequencing projects of specialized…
Updated Oct 29, 2026
HealthData.Gov
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding pro-inflammatory…
Updated Oct 29, 2026
HealthData.Gov
Objective To consider the problem of the calculation of number needed to treat (NNT) derived from risk difference, odds ratio, and raw pooled events shown to give different results using data from a review of nursing…
Updated Oct 29, 2026
HealthData.Gov
Crystalloid or colloid for resuscitation. Are we any the wiser?
Updated Oct 29, 2026
HealthData.Gov
Infective endocarditis remains a disease associated with high mortality in certain groups of patients, with death resulting primarily from central nervous system complications and congestive heart failure. Combined…
Updated Oct 29, 2026
HealthData.Gov
Background Only limited data exist on the costs of genital herpes (GH) in the USA. We estimated the economic burden of GH in the USA using two different costing approaches. Methods The first approach was a…
Updated Oct 29, 2026
HealthData.Gov
Background The purpose of this study was to investigate the association between secondhand smoke and the risk of developing a first event of acute coronary syndromes (ACS), i.e. acute myocardial infarction or unstable…
Updated Oct 29, 2026
HealthData.Gov
Thrombolysis and primary angioplasty are both recommended reperfusion strategies for elderly patients presenting with myocardial infarction (MI). Primary angioplasty is most beneficial in high-risk patients. While the…
Updated Oct 29, 2026
HealthData.Gov
Background The 13C-urea breath test (UBT) is performed in adults and children with epigastric pain for non-invasively diagnosing a suspected H. pylori infection. Criteria for UBT interpretation have not been generally…
Updated Oct 29, 2026
HealthData.Gov
Background The tissue accumulation of protein-bound advanced glycation endproducts (AGE) may be involved in the etiology of diabetic chronic complications, including osteopenia. The aim of this study was to investigate…
Updated Oct 29, 2026
HealthData.Gov
Aim: To study the effects of infusion of atrial natriuretic peptide (ANP) versus the inhalation of nitric oxide (NO) in patients with an early acute respiratory distress syndrome (ARDS). Methods: Ten patients with…
Updated Oct 29, 2026
HealthData.Gov
Background The objective of this study was to study the association of early age at menopause with pulse pressure (PP), a marker of arterial stiffness, and PP change. Methods The effect of natural menopause was studied…
Updated Oct 29, 2026
HealthData.Gov
Background The DNA single-strand annealing proteins (SSAPs), such as RecT, Redβ, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. Recently, they have been shown to form similar…
Updated Oct 29, 2026
HealthData.Gov
There is rising evidence that the initiation of atopy and asthma may occur in early life or even during fetal life. At the American Thoracic Society meeting 2001 in San Francisco, multiple reports addressed…
Updated Oct 29, 2026
HealthData.Gov
Background There has been increasing concern regarding the potential effects of the commercialization of research. Methods In order to examine the relationships between funding source, trial outcome and reporting…
Updated Oct 29, 2026
HealthData.Gov
Background The effectiveness of neoadjuvant treatment (NT) prior to resection of squamous cell carcinoma of the esophagus (SCCE) in terms of prolonged survival has not been proven by randomized trials. Facing…
Updated Oct 29, 2026
HealthData.Gov
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus may lead to inadequate…
Updated Oct 29, 2026
HealthData.Gov
Background Several neuromuscular blocking (NMB) agents are available for clinical use in anesthesia. The present study was performed in order to identify preferences and behaviors of anesthesiologists for using…
Updated Oct 29, 2026
HealthData.Gov
Background Intrathymic development and selection of the T lymphocyte repertoire is restricted by the interactions of the T cell antigen receptor and CD4 or CD8 co-receptors with self major histocompatibility complex…
Updated Oct 29, 2026
