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Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with breast cancer risk in three cohorts. In…
Updated Oct 29, 2026
HealthData.Gov
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked endogenous class II molecules to…
Updated Oct 29, 2026
HealthData.Gov
Background The first two steps in the capping of cellular mRNAs are catalyzed by the enzymes RNA triphosphatase and RNA guanylyltransferase. Although structural and mechanistic differences between fungal and mammalian…
Updated Oct 29, 2026
HealthData.Gov
Background Continuous intrathecal drug delivery has been shown in open studies to improve pain and quality of life in those with intractable back pain who have had spinal surgery. There is limited data on long term…
Updated Oct 29, 2026
HealthData.Gov
Background In this study, we investigated the mechanism(s) by which delta opioids induce their potent activation of extracellular signal-regulated protein kinases (ERKs) in different cell lines expressing the cloned…
Updated Oct 29, 2026
HealthData.Gov
Background The potential role of oral vaccination of dogs against rabies in the Philippines was investigated in terms of safety and efficacy. Methods Prior to the vaccination campaign, a house-to-house survey was…
Updated Oct 29, 2026
HealthData.Gov
Background Information on the effectiveness of elementary school level, tobacco-use prevention programs is generally limited. This study assessed the impact of a structured, one-time intervention that was designed to…
Updated Oct 29, 2026
HealthData.Gov
Nutritional support has become a routine part of the care of the critically ill patient. It is an adjunctive therapy, the main goal of which is to attenuate the development of malnutrition, yet the effectiveness of…
Updated Oct 29, 2026
HealthData.Gov
Background Bacterial infections complicate the course of patients with human immunodeficiency virus infection. The purpose of this study was to describe the bacterial pathogens causing blood stream infection, identify…
Updated Oct 29, 2026
HealthData.Gov
Background Maitotoxin (MTX) initiates cell death by sequentially activating 1) Ca2+ influx via non-selective cation channels, 2) uptake of vital dyes via formation of large pores, and 3) release of lactate…
Updated Oct 29, 2026
HealthData.Gov
Background Continuing medical education (CME) for general practitioners relies on specialist-based teaching methods in many settings. Formal lectures by specialists may not meet the learning needs of practitioners and…
Updated Oct 29, 2026
HealthData.Gov
Background Uncertainty remains about the potential harmful effects of antihypertensive therapy on the developing fetus, especially for beta-blockers (βb). Methods We prospectively enrolled all singleton women with a…
Updated Oct 29, 2026
HealthData.Gov
Background: Identification of orthologous relationships between genes from widely divergent taxa allows partial reconstruction of the gene complement of ancestral genomes. C2H2 zinc-finger genes are one of the largest…
Updated Oct 29, 2026
HealthData.Gov
Background: Various estimates of the incidence and mortality rate of the acute (adult) respiratory distress syndrome (ARDS) have been published. The studies that led to those estimates were based on relatively small…
Updated Oct 29, 2026
HealthData.Gov
Background Many eukaryotes, including plants and fungi make spores that resist severe environmental stress. The micro-organism Dictyostelium contains a single phospholipase C gene (PLC); deletion of the gene has no…
Updated Oct 29, 2026
HealthData.Gov
Background One of the major health problems among HIV seropositive patients is superimposed infection due to the defect of immunity. Furthermore, intestinal parasite infection, which is also one of the basic health…
Updated Oct 29, 2026
HealthData.Gov
Background We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to investigate whether a cluster of genes…
Updated Oct 29, 2026
HealthData.Gov
Sunlight and skin cancer
Updated Oct 29, 2026
HealthData.Gov
Background: A helium-oxygen gas mixture (heliox) has low gas density and low turbulence and resistance through narrowed airways. The effects of heliox on pulmonary mechanics following severe methacholine-induced…
Updated Oct 29, 2026
HealthData.Gov
Background Patient centred communication (PCC) has been described as a method for doctor-patient communication. The principles of shared decision making (SDM) have been proposed more recently. Aims This study aimed to…
Updated Oct 29, 2026
