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2,009 datasets

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Probing substrate binding to Metallo-β-Lactamase L1 from

Background The metallo-β-lactamases are Zn(II)-containing enzymes that hydrolyze the β-lactam bond in penicillins, cephalosporins, and carbapenems and are involved in bacterial antibiotic resistance. There are at least…

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Updated Oct 29, 2026

HealthData.Gov

Cellular responses to

Background Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would be important to determine whether there are CD4 T…

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Updated Oct 29, 2026

HealthData.Gov

Analysis of human sarcospan as a candidate gene for CFEOM1

Background Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is an autosomal dominant eye movement disorder linked to the pericentromere of chromosome 12 (12p11.2 - q12). Sarcospan is a member of the…

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Updated Oct 29, 2026

HealthData.Gov

The promise of e-Health – a Canadian perspective

Canadians value their health care system above any other social program. Canada's system of health care faces significant financial and population pressures, relating to cost, access, quality, accountability, and the…

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Updated Oct 29, 2026

HealthData.Gov

Interaction of neuronal nitric oxide synthase with alpha

Background The C-terminal four amino acids (GEEV) of human α1A-adrenergic receptors (ARs) have been reported to interact with the PDZ domain of neuronal nitric oxide synthase (nNOS) in a yeast two-hybrid system. The…

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Updated Oct 29, 2026

HealthData.Gov

Research Article: BMC Genetics

Background Blood group genotyping is increasingly utilized for prenatal diagnosis and after recent transfusions, but still lacks the specificity of serology. In whites, the presence of antigen D is predicted, if two or…

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Updated Oct 29, 2026

HealthData.Gov

Model-based cluster analysis of microarray gene-expression data

Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques have been widely applied in…

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Updated Oct 29, 2026

HealthData.Gov

Efficacy of SSH PCR in isolating differentially expressed genes

Background Suppression Subtractive Hybridization PCR (SSH PCR) is a sophisticated cDNA subtraction method to enrich and isolate differentially expressed genes. Despite its popularity, the method has not been thoroughly…

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Updated Oct 29, 2026

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