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Background Translation termination is mediated through an interaction between the release factors eRF1 and eRF3 and the stop codon within its nucleotide context. Although it is well known that the nucleotide contexts…
Updated Oct 29, 2026
HealthData.Gov
Background In Mexico, guidelines for fasting periods, or any audits on this topic are unavailable, and therefore the attitudes of anesthesiologists for recommending preoperative fasting periods are unknown. Material and…
Updated Oct 29, 2026
HealthData.Gov
Background Carpal tunnel syndrome is a common disorder, which can be treated with surgery or conservative options. However, there is insufficient evidence and no consensus among physicians with regard to the preferred…
Updated Oct 29, 2026
HealthData.Gov
Background In S. cerevisiae, the mitotic exit network (MEN) proteins, including the Polo-like protein kinase Cdc5 and the protein phosphatase Cdc14, are required for exit from mitosis. In pre-anaphase cells, Cdc14 is…
Updated Oct 29, 2026
HealthData.Gov
Background During the last decade, medium-dose UVA1 phototherapy (50 J/cm2) has achieved great value within the treatment of severe atopic dermatitis (AD). The purpose of our study was to investigate to what extent UVA1…
Updated Oct 29, 2026
HealthData.Gov
Background Linear scleroderma "en coup de sabre" (LSCS) usually affects one side of the face and head in the frontoparietal area with band-like indurated skin lesions. The disease may be associated with facial…
Updated Oct 29, 2026
HealthData.Gov
Background As novel endovascular strategies are developed for treating neurological disease, there is an increasing need to evaluate these techniques in relevant preclinical models. The use of non-human primates is…
Updated Oct 29, 2026
HealthData.Gov
Background The aim of this study was to examine the acceptability of point of care computerized prompts to improve health services delivery among a sample of primary care patients. Methods Primary data collection.…
Updated Oct 29, 2026
HealthData.Gov
Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured intracranial aneurysms (IA). Epidemiological…
Updated Oct 29, 2026
HealthData.Gov
Background: Transport of critically ill patients for diagnostic and/or therapeutic management involves significant consumption of resources. In an effort to improve the delivery of care to these patients and decrease…
Updated Oct 29, 2026
HealthData.Gov
The key question in hypertension research today is, "Does it matter how elevated blood pressure is lowered?" The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) initiated in 1994…
Updated Oct 29, 2026
HealthData.Gov
Background The Resource Dispersion Hypothesis (RDH) proposes a mechanism for the passive formation of social groups where resources are dispersed, even in the absence of any benefits of group living per se. Despite…
Updated Oct 29, 2026
HealthData.Gov
Background: Cohesin is a macromolecular complex that links sister chromatids together at the metaphase plate during mitosis. The links are formed during DNA replication and destroyed during the metaphase-to-anaphase…
Updated Oct 29, 2026
HealthData.Gov
Cell transplantation to repair or regenerate injured myocardium is a new frontier in the treatment of cardiovascular disease. Even though it is based on many years of pre-clinical studies, much remains to be understood…
Updated Oct 29, 2026
HealthData.Gov
Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has identified over 217 candidate overlapping…
Updated Oct 29, 2026
HealthData.Gov
Background The proportion of older patients in cardiac surgery is continuously increasing. 37% of patients undergoing heart surgery in Germany in the year 2000 were 70 years of age and older. We have studied the role of…
Updated Oct 29, 2026
HealthData.Gov
The fair innings argument (FIA) is frequently put forward as a justification for denying elderly patients treatment when they are in competition with younger patients and resources are scarce. In this paper I will…
Updated Oct 29, 2026
HealthData.Gov
Background The ubiquitin-dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitinating enzymes constitute a complex protein family involved in a…
Updated Oct 29, 2026
HealthData.Gov
Introduction The administration of antithrombin III (ATIII) is useful in patients with congenital deficiency, but evidence for the other therapeutic indications of this drug is still uncertain. In Italy, the use of…
Updated Oct 29, 2026
HealthData.Gov
Background A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe pair and calculates model-based…
Updated Oct 29, 2026
