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The ethics of health sector databases
The ethics of health sector databases
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Updated Oct 29, 2026
Datasets
2,009 datasets
HealthData.Gov
p53 in rheumatoid arthritis: friend or foe?
The knowledge of transcription factors and proto-oncogenes has influenced the understanding of cell regulation, cell cycle, and apoptotic cell death in rheumatoid arthritis (RA) synovium. In addition, the development of…
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Updated Oct 29, 2026
HealthData.Gov
Maitotoxin-induced membrane blebbing and cell death in bovine aortic endothelial cells
Background Maitotoxin, a potent cytolytic agent, causes an increase in cytosolic free Ca2+ concentration ([Ca2+]i) via activation of Ca2+-permeable, non-selective cation channels (CaNSC). Channel activation is followed…
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Updated Oct 29, 2026
HealthData.Gov
Manipulation of the follicular phase: Uterodomes and pregnancy - is there a correlation?
Background Manipulation of the follicular phase uterine epithelium in women undergoing infertility treatment, has not generally shown differing morphological effects on uterine epithelial characteristics using Scanning…
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Updated Oct 29, 2026
HealthData.Gov
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression is poorly understood, but previous findings have…
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Updated Oct 29, 2026
HealthData.Gov
Are the Cochrane group registers comprehensive? A case study of Japanese psychiatry trials
Background Language bias is a form of publication bias and constitutes a serious threat to meta-analyses. The Cochrane Controlled Trials Register is one attempt to remedy this and now contains more than 300,000…
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Updated Oct 29, 2026
HealthData.Gov
Epithelial antimicrobial peptides in host defense against infection
One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their structure and amino acid motifs. Peptides of the…
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Updated Oct 29, 2026
HealthData.Gov
On the probability of cost-effectiveness using data from randomized clinical trials
Background Acceptability curves have been proposed for quantifying the probability that a treatment under investigation in a clinical trial is cost-effective. Various definitions and estimation methods have been…
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Updated Oct 29, 2026
HealthData.Gov
Cross-sectional study of morbidity, morbidity-associated factors and cost of treatment in Ngaoundere, Cameroon, with implications for health policy in developing countries and development assistance policy
Background In a population-based epidemiological study in Ngaoundere, Cameroon, we studied cross-sectional child morbidity and the cost of necessary investigation and treatment. Methods Three teams of two to three…
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Updated Oct 29, 2026
HealthData.Gov
Penis size: Survey of female perceptions of sexual satisfaction
Background Does the size of the male penis, in terms of length or width, make a difference in female sexual satisfaction? Method To study the effect of penis width vs. length on female sexual satisfaction, 50 sexually…
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Updated Oct 29, 2026
HealthData.Gov
Reinforcement of genetic coherence in a two-locus model
Background In order to maintain populations as units of reproduction and thus enable anagenetic evolution, genetic factors must exist which prevent continuing reproductive separation or enhance reproductive contact.…
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Updated Oct 29, 2026
HealthData.Gov
Patterns in abundance and diversity of faecally dispersed parasites of tiger in Tadoba National Park, central India
Background Importance of parasites in ecological and evolutionary interactions is being increasingly recognized. However, ecological data on parasites of important host species is still scanty. We analyze the patterns…
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Updated Oct 29, 2026
HealthData.Gov
Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R
Background Vaccinia virus gene B1R encodes a serine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R, proteins that become phosphorylated…
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Updated Oct 29, 2026
HealthData.Gov
Verbal autopsy of 48 000 adult deaths attributable to medical causes in Chennai (formerly Madras), India
Background In the city of Chennai, India, registration of the fact of death is almost complete but the cause of death is often inadequately recorded on the death certificate. A special verbal autopsy (VA) study of 48…
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Updated Oct 29, 2026
HealthData.Gov
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer
Background The objective of the present study was to examine the prognostic and predictive significance of the apoptosis-related marker Fas ligand (FasL):Fas ratio in breast cancer. Methods Tumour biopsies from 215…
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Updated Oct 29, 2026
HealthData.Gov
Commentary on "Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus", by RR Graham
Genome-wide linkage analysis studies in families with systemic lupus erythematosus (SLE) have revealed consistent evidence of linkage to several regions of the genome. In a previous issue of this journal, Graham and…
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Updated Oct 29, 2026
HealthData.Gov
Cell-cell interactions in synovitis: Endothelial cells and immune cell migration
Leukocyte ingress into the synovium is a key process in the pathogenesis of rheumatoid arthritis and other inflammatory conditions. In this review, the role of endothelial cells in leukocyte extravasation will be…
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Updated Oct 29, 2026
HealthData.Gov
"Bronchial Artery Delivery of Viral Vectors for Gene delivery in Cystic Fibrosis; Superior to Airway Delivery?"
Background Attempts at gene therapy for the pulmonary manifestations of Cystic Fibrosis have relied mainly on airway delivery. However the efficiency of gene transfer and expression in the airway epithelia has not…
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Updated Oct 29, 2026
HealthData.Gov
Organisational development in general practice: lessons from practice and professional development plans (PPDPs)
Background Improving the quality and effectiveness of clinical practice is becoming a key task within all health services. Primary medical care, as organised in the UK is composed of clinicians who work in independent…
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Updated Oct 29, 2026
HealthData.Gov
Microscopy of bacterial translocation during small bowel obstruction and ischemia in vivo – a new animal model
Background Existing animal models provide only indirect information about the pathogenesis of infections caused by indigenous gastrointestinal microflora and the kinetics of bacterial translocation. The aim of this…
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Updated Oct 29, 2026