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HealthData.Gov

Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer

Background Genome-wide or application-targeted microarrays containing a subset of genes of interest have become widely used as a research tool with the prospect of diagnostic application. Intrinsic variability of…

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Updated Oct 29, 2026

HealthData.Gov

Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios

Background The power of DNA microarrays derives from their ability to monitor the expression levels of many genes in parallel. One of the limitations of such powerful analytical tools is the inability to detect certain…

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Updated Oct 29, 2026