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p53 performs a plethora of activities, which are directed towards the maintenance of the genomic integrity and constitute its universal role as a tumor suppressor. 1000 to 10000 latent p53 molecules are permanently…
Updated Oct 29, 2026
HealthData.Gov
Background It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively studied in type 1 diabetes, but not…
Updated Oct 29, 2026
HealthData.Gov
Background: Protein fold recognition using sequence profile searches frequently allows prediction of the structure and biochemical mechanisms of proteins with an important biological function but unknown biochemical…
Updated Oct 29, 2026
HealthData.Gov
Some provocative thoughts on damage and repair of DNA
Updated Oct 29, 2026
