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HealthData.Gov

Debate: The potential role of estrogen in the prevention of heart disease in women after menopause

Large numbers of observational studies have described a decrease in the incidence of cardiovascular disease in women taking hormone replacement therapy (HRT). The potential mechanisms for this effect are numerous,…

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Updated Oct 29, 2026

HealthData.Gov

Debate: The potential role of estrogen in the prevention of heart disease in women after menopause

The observational studies of hormone users are compromised by systematic biases that lead to an overestimation of benefit and an underestimation of risk. Studies of mechanism could support either benefit or harm. The…

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Updated Oct 29, 2026