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HealthData.Gov

PKQuest: measurement of intestinal absorption and first pass metabolism – application to human ethanol pharmacokinetics

Background PKQuest, a new physiologically based pharmacokinetic (PBPK) program, is applied to human ethanol data. The classical definition of first pass metabolism (FPM) based on the differences in the area under the…

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Updated Oct 29, 2026

HealthData.Gov

Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats

Background It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal muscle. Methods To evaluate the…

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Updated Oct 29, 2026