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The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for…
Updated Oct 29, 2026
HealthData.Gov
The human lysosomal cysteine proteases are a family of 11 proteases whose members include cathepsins B, C, H, L, and S. The biology of these proteases was largely ignored for decades because of their lysosomal location…
Updated Oct 29, 2026
HealthData.Gov
Pulmonary surfactant is a complex mixture of phospholipids and proteins, which is present in the alveolar lining fluid and is essential for normal lung function. Alterations in surfactant composition have been reported…
Updated Oct 29, 2026
HealthData.Gov
Focusing on diffuse (interstitial) lung disease: a rapidly evolving field
Updated Oct 29, 2026
HealthData.Gov
Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may…
Updated Oct 29, 2026
