Datasets

8 datasets

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HealthData.Gov

Evidence for large domains of similarly expressed genes in the

Background Transcriptional regulation in eukaryotes generally operates at the level of individual genes. Regulation of sets of adjacent genes by mechanisms operating at the level of chromosomal domains has been…

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Updated Oct 29, 2026

HealthData.Gov

Model-based cluster analysis of microarray gene-expression data

Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques have been widely applied in…

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Updated Oct 29, 2026

HealthData.Gov

Design and implementation of microarray gene expression markup language (MAGE-ML)

Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same format from one publication to another. MAGE will help…

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Updated Oct 29, 2026

HealthData.Gov

A simple method for statistical analysis of intensity differences in microarray-derived gene expression data

Background Microarray experiments offer a potent solution to the problem of making and comparing large numbers of gene expression measurements either in different cell types or in the same cell type under different…

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Updated Oct 29, 2026

HealthData.Gov

Permutation-validated principal components analysis of microarray data

Background In microarray data analysis, the comparison of gene-expression profiles with respect to different conditions and the selection of biologically interesting genes are crucial tasks. Multivariate statistical…

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Updated Oct 29, 2026

HealthData.Gov

Profound effect of normalization on detection of differentially expressed genes in oligonucleotide microarray data analysis

A number of procedures for normalization and detection of differentially expressed genes have been proposed. Four different normalization methods and all possible combinations with three different statistical algorithms…

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Updated Oct 29, 2026

HealthData.Gov

Vector algebra in the analysis of genome-wide expression data

Background Data from thousands of transcription-profiling experiments in organisms ranging from yeast to humans are now publicly available. How best to analyze these data remains an important challenge. A variety of…

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Updated Oct 29, 2026

HealthData.Gov

Mining microarray expression data by literature profiling

The lack of efficient techniques for assessing the biological implications of microarray gene-expression data remains an important obstacle in exploiting this information. To address this need, a mining technique has…

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Updated Oct 29, 2026