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Background Inhibitor of Apoptosis (IAP) proteins are key intrinsic regulators of apoptosis induced by a variety of triggers. We isolated the rat Inhibitor of Apoptosis genes 1, 2 and 3 and characterized their tissue…
Updated Oct 29, 2026
HealthData.Gov
Background Balloon injury (BI) of the rat carotid artery (CCA) is widely used to study intimal hyperplasia (IH) and decrease in lumen diameter (LD), but CCA's small diameter impedes the evaluation of endovascular…
Updated Oct 29, 2026
HealthData.Gov
Background The possible participation of diesel exhaust inhalation during the fetal period in the elevation of IgE against pollen in postnatal life was investigated. Method The experiment was conducted using rat pups.…
Updated Oct 29, 2026
HealthData.Gov
Background Although much is known about the regulation of osteoclast (OC) formation and activity, little is known about OC senescence. In particular, the fate of of OC seen after 1,25-(OH)2D3 administration in vivo is…
Updated Oct 29, 2026
HealthData.Gov
The kinetics of apoptosis and the apoptosis-regulating gene p53 in adjuvant arthritis (AA) were investigated to assess the value of the AA rat model for testing apoptosis-inducing therapies. Very few terminal…
Updated Oct 29, 2026
HealthData.Gov
Background Our aim was to explore the de-addiction properties of Delphinium denudatum Wall. in morphine dependent rats. Methods Charles Foster male albino rats were made morphine dependent by injecting morphine sulphate…
Updated Oct 29, 2026
HealthData.Gov
Background Pancreatic cancer is a biologically aggressive disease with less than 20% of patients suitable for a "curative" surgical resection. This, combined with the poor 5-year survival indicates that effective…
Updated Oct 29, 2026
HealthData.Gov
Background Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences…
Updated Oct 29, 2026
HealthData.Gov
Background Little information is available on the circadian sequela of an immune challenge in the brain of aged rats. To assess them, we studied 24-hour rhythms in hypothalamic and striatal norepinephrine (NE) content,…
Updated Oct 29, 2026
