Datasets

2 datasets

HealthData.Gov

Identification of critical residues in loop E in the 5-HT

Background The serotonin type 3 receptor (5-HT3R) is a member of a superfamily of ligand gated ion channels. All members of this family share a large degree of sequence homology and presumably significant structural…

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Updated Oct 29, 2026

HealthData.Gov

Functional group interactions of a 5-HT

Background Lerisetron, a competitive serotonin type 3 receptor (5-HT3R) antagonist, contains five functional groups capable of interacting with amino acids in the 5-HT3R binding site. Site directed mutagenesis studies…

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Updated Oct 29, 2026