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DNA microarrays were used to examine the temporal program of gene expression following treatment of a human prostate cancer cell line with androgen. Significant changes in levels of transcripts of more than 500 genes…
Updated Oct 29, 2026
HealthData.Gov
A combination of linear RNA amplification and DNA microarray hybridization has allowed the determination of expression profiles of individual imaginal discs and larval tissues and the identification of genes expressed…
Updated Oct 29, 2026
HealthData.Gov
Background Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in somatic cell hybrids to analyze genes responsible for…
Updated Oct 29, 2026
HealthData.Gov
A simple and robust non-linear method is presented for normalization using array signal distribution analysis and cubic splines. Both the regression and spline-based methods described performed better than existing…
Updated Oct 29, 2026
HealthData.Gov
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression levels changed from one treatment group to the next,…
Updated Oct 29, 2026
