Datasets

4 datasets

HealthData.Gov

Multiple redundant sequence elements within the fission yeast

Background Some origins in eukaryotic chromosomes fire more frequently than others. In the fission yeast, Schizosaccharomyces pombe, the relative firing frequencies of the three origins clustered 4-8 kbp upstream of the…

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Updated Oct 29, 2026

HealthData.Gov

Asymmetric directional mutation pressures in bacteria

When there are no strand-specific biases in mutation and selection rates between the two strands of DNA, the average nucleotide composition is theoretically expected to be A = T and G = C within each strand. By focusing…

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Updated Oct 29, 2026

HealthData.Gov

Stress responses and replication of plasmids in bacterial cells

Plasmids, DNA (or rarely RNA) molecules which replicate in cells autonomously (independently of chromosomes) as non-essential genetic elements, play important roles for microbes grown under specific environmental…

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Updated Oct 29, 2026

HealthData.Gov

Reconstitution of licensed replication origins on

Background In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA…

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Updated Oct 29, 2026