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Background Decisions on treatment are guided, not only by the potential for benefit, but also by the nature and severity of adverse drug reactions. However, some researchers have found numerous deficiencies in trial…
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Background We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may…
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Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a new drug, placebo or active control drugs by pooling…
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Mometasone Furoate is a corticosteroid nasal spray used to relieve symptoms of seasonal and year-round allergies, such as nasal congestion, runny nose, and sneezing. Available over-the-counter under brands like Nasonex…
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Fiasp is a fast-acting insulin aspart injection used to control blood sugar levels in people with diabetes. Manufactured by Novo Nordisk, it's available as a subcutaneous solution in pens and cartridges, with strengths…
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Brenzavvy (bexagliflozin) is a prescription oral tablet used to manage type 2 diabetes by lowering blood sugar levels. As an SGLT2 inhibitor, it helps the kidneys remove excess glucose through urine. Available in 20 mg…
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Pregabalin Extended Release is a generic prescription drug containing pregabalin, available as oral extended-release tablets in strengths of 82.5 mg, 165 mg, and 330 mg. Manufactured by ScieGen Pharmaceuticals under…
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Caspofungin Acetate is an antifungal medication used to treat serious fungal infections. It belongs to the echinocandin class and is administered intravenously as a powder that is mixed into a solution. Available in 50…
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Triamcinolone Acetonide is a prescription corticosteroid ointment (0.5% strength) applied topically to reduce inflammation and itching from skin conditions. Manufactured by Glenmark Pharmaceuticals Inc., USA, under…
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Incassia is a prescription oral tablet containing 0.35 mg of norethindrone, a progestin hormone. It's used for birth control to prevent pregnancy by regulating menstrual cycles. Manufactured by Aurobindo Pharma, it's…
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Thioridazine Hydrochloride is a generic prescription drug available as 10 mg film-coated tablets for oral use. Manufactured by Chartwell RX, LLC under application ANDA088131, it belongs to the phenothiazine class and is…
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Mexiletine Hydrochloride is a prescription antiarrhythmic medication used to treat certain heart rhythm disorders. Available as oral capsules in 150mg, 200mg, and 250mg strengths, it's manufactured by Leading Pharma,…
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Amitriptyline Hydrochloride is a prescription medication available as oral tablets in strengths of 10mg, 25mg, 50mg, 75mg, 100mg, and 150mg. It is a tricyclic antidepressant used to treat conditions like depression.…
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VANFLYTA (quizartinib) is an oral prescription tablet developed by Daiichi Sankyo Inc. for treating certain blood cancers. It works as a kinase inhibitor targeting FLT3 mutations, available in 17.7 mg and 26.5 mg…
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Ganirelix Acetate is a prescription injectable medication used to prevent premature ovulation in women undergoing fertility treatments. It works by blocking certain hormones and is administered subcutaneously.…
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Abiraterone Acetate is a prescription oral tablet with 250 mg of the active ingredient, used to treat metastatic castration-resistant prostate cancer in men. It's a generic version manufactured by Rising Pharma…
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Chlorpromazine Hydrochloride is a generic prescription medication used to treat psychotic disorders like schizophrenia and bipolar disorder. It comes as 25 mg film-coated oral tablets, manufactured by Upsher-Smith…
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Tazarotene is a prescription topical gel containing 0.1% tazarotene, a retinoid medication. Manufactured by Cosette Pharmaceuticals, Inc., it's used for certain skin conditions and comes in 30g or 100g tubes. This…
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Hemabate (carboprost tromethamine) is a prescription injectable medication used intramuscularly to control postpartum bleeding. Manufactured by Pharmacia & Upjohn Company LLC, it comes as a 250 mcg/mL solution in…
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Bumetanide is a prescription loop diuretic that helps remove excess fluid from the body by increasing urine production at the kidneys' loop of Henle. Available as oral tablets in 0.5 mg, 1 mg, and 2 mg strengths, it's…