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The observational studies of hormone users are compromised by systematic biases that lead to an overestimation of benefit and an underestimation of risk. Studies of mechanism could support either benefit or harm. The…
Updated Oct 29, 2026
HealthData.Gov
Background Hormone replacement therapy (HRT) is often seen as the treatment of choice for preventing fractures in women. We undertook a recent meta-analysis of randomised trials which suggested that HRT reduced…
Updated Oct 29, 2026
HealthData.Gov
Background Information regarding the characteristics and health of women who do and do not attend for breast cancer screening is limited and representative data are difficult to obtain. Methods Information on age,…
Updated Oct 29, 2026
HealthData.Gov
Background It is known that use of hormone replacement therapy (HRT) by postmenopausal women increases the risk of breast cancer. Method In this study, oestrogen receptor (ER)-α expression is examined using standard…
Updated Oct 29, 2026
HealthData.Gov
Large numbers of observational studies have described a decrease in the incidence of cardiovascular disease in women taking hormone replacement therapy (HRT). The potential mechanisms for this effect are numerous,…
Updated Oct 29, 2026
