Datasets

2 datasets

HealthData.Gov

TNF-α induced endothelial MAdCAM-1 expression is regulated by exogenous, not endogenous nitric oxide

Background MAdCAM-1 is an adhesion molecule expressed in Peyer's patches and lymphoid tissues which is mobilized by cytokines like TNF-α and is a major determinant of lymphocyte trafficking to the gut in human…

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Updated Oct 29, 2026

HealthData.Gov

Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.

Background Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of inflammatory bowel disease (IBD). Melatonin, a relatively safe,…

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Updated Oct 29, 2026