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We are delighted to welcome you to the first printed issue ofArthritis Research, a publication that has already existed on the Internet for the last few months. This fact alone is an indication that we are beginning a…
Updated Oct 29, 2026
HealthData.Gov
During our careers, we have developed new and innovative concepts pertaining to the pathophysiology of osteoarthritis which have assisted in the development of new therapeutic approaches. Moreover, our laboratory has…
Updated Oct 29, 2026
HealthData.Gov
Cartilage contains numerous noncollagenous proteins in its extracellular matrix, including proteoglycans. At least 40 such molecules have been identified, differing greatly in structure, distribution, and function. Some…
Updated Oct 29, 2026
HealthData.Gov
Chromosomal aberrations were comparatively assessed in nuclei extracted from synovial tissue, primary-culture (P-0) synovial cells, and early-passage synovial fibroblasts (SFB; 98% enrichment; P-1, P-4 [passage 1,…
Updated Oct 29, 2026
HealthData.Gov
Angiopoietins (Ang) are vascular endothelial cell-specific growth factors that play important roles principally during the later stages of angiogenesis. We have compared the distribution of the receptor tyrosine kinase…
Updated Oct 29, 2026
HealthData.Gov
Clinical practice guidelines are important tools to assist clinical decision-making. Recently, several guidelines addressing the management of osteoarthritis (OA) have been published. Clinicians treating patients with…
Updated Oct 29, 2026
HealthData.Gov
Background It has been reported that there is an inverse association between osteoarthritis (OA) and osteoporosis. However, the relationship of bone mass to OA in a Japanese population whose rates of OA are different…
Updated Oct 29, 2026
HealthData.Gov
While many proteases in articular cartilage have been described, current studies indicate that members of two families of metalloproteases – MMPs and the ADAMTSs – are responsible for the degradation of the major…
Updated Oct 29, 2026
