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Background Little empirical research has examined the multiple consequences of osteoporosis on quality of life. Methods Health related quality of life (HRQL) was examined in relationship to incident fractures in 2009…
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Bone loss occurs when the cellular events of bone formation are quantitatively larger than bone formation. This manuscript discusses the measurement of bone loss, occurrence in the population, risk factors and…
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Background The identification of new methods of evaluating patients with osteoporotic fracture should focus on their usefulness in clinical situations such that they are easily measured and applicable to all patients.…
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Background Hormone replacement therapy (HRT) is often seen as the treatment of choice for preventing fractures in women. We undertook a recent meta-analysis of randomised trials which suggested that HRT reduced…
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Rheumatoid arthritis represents an excellent model in which to gain insights into the local and systemic effects of joint inflammation on skeletal tissues. Three forms of bone disease have been described in rheumatoid…
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The SWAN Repository is the biospecimen bank of the SWAN study. All stored specimens are from the 3,302 SWAN participants, collected across the 14 clinic visits (Baseline and 13 follow-up visits). Available biospecimen…
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The SWAN Public Use Datasets provide access to longitudinal data describing the physical, biological, psychological, and social changes that occur during the menopausal transition. Data collected from 3,302 SWAN…
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The SWAN Coordinating Center provides SWAN data access to SWAN Investigators through the study website. The SWAN website provides access to longitudinal data describing the physical, biological, psychological, and…