Datasets

2 datasets

HealthData.Gov

Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes

Background Lysosomes are acidic organelles that play multiple roles in various cellular oxidative activities such as the oxidative burst during cytotoxic killing. It remains to be determined how lysosomal lumen…

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Updated Oct 29, 2026

HealthData.Gov

Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of K

Background Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in cellular functions. Accumulating lines of evidence…

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Updated Oct 29, 2026