Datasets

2 datasets

HealthData.Gov

The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator

Background Endoplasmic reticulum retention of misfolded cystic fibrosis transmembrane conductance regulator (CFTR) mutants and their rapid degradation is the major cause of cystic fibrosis (CF). An important goal is to…

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Updated Oct 29, 2026

HealthData.Gov

Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase

Background Setting of graded levels of a protein for in vivo studies by controlled gene expression has inconveniences, and we here explore the use of the t-degron technique instead. Results In a yeast t-degron…

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Updated Oct 29, 2026