Datasets

3 datasets

HealthData.Gov

Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I

Background Two-hybrid screening for proteins that interact with the core domain of human topoisomerase I identified two novel proteins, BTBD1 and BTBD2, which share 80% amino acid identities. Results The interactions…

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Updated Oct 29, 2026

HealthData.Gov

Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions

Background It has recently been shown that the detection of gene fusion events across genomes can be used for predicting functional associations of proteins, including physical interaction or complex formation. To…

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Updated Oct 29, 2026

HealthData.Gov

Itt1p, a novel protein inhibiting translation termination in

Background Termination of translation in eukaryotes is controlled by two interacting polypeptide chain release factors, eRFl and eRF3. eRFl recognizes nonsense codons UAA, UAG and UGA, while eRF3 stimulates polypeptide…

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Updated Oct 29, 2026