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Although early antibiotic treatment of patients with septic arthritis eradicates bacteria, joint destruction commonly results from the unregulated host inflammatory responses to infection. The spin trap compound…
Updated Oct 29, 2026
HealthData.Gov
A possible cause of joint destruction in septic arthritis
Updated Oct 29, 2026
HealthData.Gov
Staphylococcus aureus is one of the most important pathogens in septic arthritis. To analyse the arthritogenic properties of staphylococcal peptidoglycan (PGN), highly purified PGN from S. aureus was intra-articularly…
Updated Oct 29, 2026
HealthData.Gov
The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs, because of lack of IL-12.…
Updated Oct 29, 2026
HealthData.Gov
Weight loss is typically found during severe infections, e.g. septic arthritis. The aim of our study was to evaluate the role of leptin, regulator of food intake and energy expenditure, for the development of…
Updated Oct 29, 2026
