Datasets

2 datasets

HealthData.Gov

T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis

The immunodominant T-cell epitope that is involved in collagen-induced arthritis (CIA) is the glycosylated type II collagen (CII) peptide 256-270. In CII transgenic mice, which express the immunodominant CII 256-270…

HTML

Updated Oct 29, 2026

HealthData.Gov

The role of X-chromosome inactivation in female predisposition to autoimmunity

We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus may lead to inadequate…

HTML

Updated Oct 29, 2026