Datasets

2 datasets

HealthData.Gov

Methylation and silencing of the retinoic acid receptor-β2 gene in cervical cancer

Background Expression of the retinoic acid receptor β2 (RAR-β2), a putative tumor suppressor gene, is reduced in various human cancers, including squamous cell carcinomas (SCC) of the uterine cervix. The mechanism of…

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Updated Oct 29, 2026

HealthData.Gov

Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor

Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous PTEN was able to suppress their…

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Updated Oct 29, 2026